Diagnosis of CLIPPERS is challenging, and requires careful exclusion of alternative diagnoses. Brain.

Clipboard, Search History, and several other advanced features are temporarily unavailable. The disorder usually readily responds to immunosuppression with … MRI findings in CLIPPERS show a very striking and characteristic lesion pattern and a high degree of similarity among affected individuals. This site needs JavaScript to work properly.

2019 Nov 4;19(1):266. doi: 10.1186/s12883-019-1507-z.Vola E, Russo C, Macera A, Del Vecchio W, Puoti G, Caranci F, Elefante A.Eur J Radiol Open.

2019 Feb 1;6(3):e545. © The Author (2017). Following its initial description, the salient features of CLIPPERS have been confirmed and expanded upon, but the lack of formalized diagnostic criteria has led to … Objective: To describe a cohort of patients with suspected CLIPPERS. Описан случай синдрома CLIPPERS у пациента 56 лет, проживающего в Западной Сибири. Epub 2020 Jan 10.Curr Neurol Neurosci Rep. 2019 Nov 26;19(12):95. doi: 10.1007/s11910-019-1015-y.Nervenarzt. Published by Oxford University Press on behalf of the Guarantors of Brain. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an uncommon and only recently described disorder characterized by infiltration of the brain by inflammatory cells. 2010 Sep;133(9):2626-34. doi: 10.1093/brain/awq164. masuzi December 27, 2019 Uncategorized 0.

Wang X, Huang D, Huang X, Zhang J, Ran Y, Lou X, Gui Q, Yu S.J Neuroimmunol. The protocol should include contrast. Please enable it to take advantage of the complete set of features! A specific serum or cerebrospinal fluid (CSF) biomarker for the disorder is currently not known. 2017 Feb;62(1):28-33. doi: 10.1177/0036933016689006. This paper presents a brief literature review on chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) syndrome.

2015 Dec;84(6):2077.e1-3. The condition features a combination of clinical symptoms essentially referable to brainstem pathology and a characteristic magnetic resonance imaging (MRI) appearance with punctate and curvilinear gadolinium enhancement 'peppering' the pons. Neuroimaging and neuropathology were reviewed by experienced neuroradiologists and neuropathologists, respectively, both of whom were blinded to the clinical data. Epub 2017 Jan 26.Dudesek A, Rimmele F, Tesar S, Kolbaske S, Rommer PS, Benecke R, Zettl UK.Clin Exp Immunol. Corticosteroids may first be taken intravenously (by IV) for several days, and then orally.


Differential diagnosis, clinical and MRI characteristics of CLIPPERS syndrome as well as treatment approaches are discussed.

2019 Jun 6;6:212-214. doi: 10.1016/j.ejro.2019.05.005. eCollection 2020 Jun.Bot JCJ, Mazzai L, Hagenbeek RE, Ingala S, van Oosten B, Sanchez-Aliaga E, Barkhof F.Neuroradiology. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a CNS inflammatory disorder characterized by pontine predominant, punctate, gadolinium enhancing MRI lesions with exquisite response to corticosteroid therapy (Pittock et al., 2010). CLIPPERS patients had brainstem predominant perivascular gadolinium enhancing lesions on magnetic resonance imaging that were discriminated from non-CLIPPERS by: homogenous gadolinium enhancing nodules <3 mm in diameter without ring-enhancement or mass effect, and homogenous T2 signal abnormality not significantly exceeding the T1 enhancement.

2020 Mar;62(3):283-300. doi: 10.1007/s00234-019-02335-5. 2020 Mar;62(3):283-300. doi: 10.1007/s00234-019-02335-5. Wiley Brain magnetic resonance imaging (MRI) of a patient with CLIPPERS (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) (coronar post-contrast T1-weighted images). Please enable it to take advantage of the complete set of features! Objective: To describe two cases of a supratentorial variant of CLIPPERS we propose to call SLIPPERS Background: Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder characterized by a combination of clinical symptoms correlating to magnetic resonance gadolinium enhancing lesions of the pons. Free PMC article The authors present a case of a 56-year old patient with CLIPPERS syndrome in West Siberia.
doi: 10.1093/brain/awx336.Brain.

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2017 Oct;17:95-98. doi: 10.1016/j.msard.2017.07.012.

Print 2019 Nov.

Corticosteroid responsiveness was common but not universal in non-CLIPPERS [clinical improvement (8/12); radiological improvement (2/12); clinical worsening on discontinuation (3/8)]. no beading) are reported Susceptibility weighted imaging can reveal prominent veins and punctate regions of signal loss Patients typically respond rapidly to the administration of glucocorticosteroids but have a tendency to relapse if immunosuppression is ceased.

Silverchair Information Systems 2018 Jan 1;141(1):e6.


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